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Project PRISM is a randomized controlled trial evaluating a self-guided digital therapeutic: (DTx) Amplification of Positivity – Cannabis Use Disorder (AMP-C). This DTx was designed to target reward dysfunction, a common deficit in those with both Cannabis Use Disorder (CUD) and Major Depressive Disorder (MDD). AMP-C was developed in collaboration with individuals who have lived experiences with cannabis use and depression symptoms. We hope that this study will provide us with information on the efficacy of AMP-C and guide the development of more effective, scalable methods for treating co-occurring CUD and MDD.
What is AMP-C?
Amplification of Positivity – Cannabis Use Disorder (AMP-C) is an app-based intervention that was designed by adapting an evidence-based psychotherapy, Amplification of Positivity, which has demonstrated efficacy in reducing substance use, depression, and anxiety. AMP-C includes several modules that focus on understanding the link between cannabis use and depressive symptoms and offer strategies to boost positive emotions. Each module of AMP-C includes 2-4 brief psychoeducation videos and activities. By engaging with AMP-C, you may develop adaptive skills to increase your positive emotions and behaviors while also decreasing your cannabis use and depressive symptoms.
Interested in participating in our study? Take this 2-minute survey to see if you are eligible to participate:
Cannabis Use Disorder
Cannabis Use Disorder (CUD) is a type of substance use disorder and mental health condition. It is marked by a problematic pattern of cannabis use that causes distress or difficulties in daily life. People with CUD may experience a strong urge to use cannabis, a tolerance to its effects, or withdrawal symptoms when trying to stop. CUD may interfere with your health, relationships and how you feel day to day.
Major Depressive Disorder
Major depressive disorder (MDD) is a type of mood disorder marked by lasting feelings of sadness and a reduced interest in once enjoyable activities. MDD is different than just experiencing sadness. People with MDD experience a range of symptoms that occur nearly every day for at least two weeks and can include difficulties sleeping and eating. People with MDD often experience difficulties with their daily functioning that may impact their work, home, or social lives.
As of 2023:
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25.9% of adults aged 18+ used marijuana in the past month
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7% of adults aged 18+ were diagnosed with having cannabis use disorder, specifically, 18-25 years old, 16.6% of the population have cannabis use disorder
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Among those with cannabis use disorder aged 18+, 52.5% of them had a co-occurring mental illness
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Among those with cannabis use disorder aged 18+, 24% of them had a major depressive episode in the last year
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8.5% of adults aged 18+ had a major depressive episode in the past year, specifically, 18-25 years olds, 17.5% of the population had a major depressive episode in the past year
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